In the recent NinjaCast: Design Considerations (by Mel Vale) he recommended setting up a design grid. Here is an example of a 3 column, 5 row design grid.
This allows you to align and size the various widgets in your Template. While this seems fine initially, in use, the underlying Background grid means that you don't always snap to the Design grid. It also leaves a lot of Widgets in the template that can slow down Report & Dashboard creation.
What's the ideal solution?
Here is an example of what the New Template Settings could look like, which would include the ability to define the Background Grid.
What's a reasonable solution?
Allow Template designers to turn off the background/underlying grid.